The computational fluid dynamics model of the in-vivo human lens

Jul 31, 2018Physiological optics of the eye, Research, Technology & Vision

The human lens is a major optical component that contributes to overall vision. Fluid dynamics and physiology of the lens change as we age, which leads to the formation of diseases such as cataract. In this project, I have focused on creating aging human lens computer models which incorporate important anatomical landmarks of the eye such as the anterior chamber, the iris, and the vitreous cavity.

This is the first model of its kind to include all the anatomical features of the anterior eye. The model accurately simulates velocities, pressures and ionic concentration gradients, which have been previously modelled or measured. We are planning to use this model to create a better understanding of cataract onset.

Author: Ho Ting Duncan Wu


Collaborators: Dr Ehsan Vaghefi, Prof Paul Donaldson

Funding details: HRC Emerging Researcher Grant

Status: Published