Studying the Effects of Ultraviolet-A Radiation on the Crystalline Lens
Several factors contribute to the ageing of the eye over a lifetime, leading to visual impairments. One of these factors is ultraviolet-A (UVA, 320-400nm) radiation, which influences the crystalline lens in particular.
First, annual dosages were calculated based on various factors (latitude, altitude, etc) and scaled according to what percentage reached the crystalline lens. Next, this dosage was replicated on an experimental lens system. The crystalline lenses was imaged before and after the dosage, using the previously assembled Laser Ray Tracing (LRT) system. The LRT system is used to determine optical properties.
The data showed a change in the shape and geometry of the lens. Also, the components of the lens were altered such that the refractive index values changed. Refractive index values determine how light bends through the lens.
Author: Carrie Burgess
Collaborators: Dr Ehsan Vaghefi
Funding details: Marsden Project fund
Status: Funded and running