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Studying the effects of ageing on intravitreal drug administration using bi-modal modelling approach

Studying the effects of ageing on intravitreal drug administration using bi-modal modelling approach

by nata004 | Jul 31, 2018 | Ageing Vision, Physiological optics of the eye, Research

Age-related macular degeneration (AMD) is the leading cause of blindness in New Zealand, affecting 184,000 people in 2014, costing $391.1 million in 2016, or $19,825 per patient. Anti-VEGF injection is the most effective way to control AMD progression, which is...
MRI of blood perfusion for ischemic retinal diseases

MRI of blood perfusion for ischemic retinal diseases

by nata004 | Jul 31, 2018 | Ageing Vision, Physiological optics of the eye, Research

Retinal ischemia plays a significant role in the pathogenesis of age-related macular degeneration (AMD) and Diabetic Retinopathy (DR) — two of the most common sight-threatening diseases in the developed world. Treatments for these conditions are limited, and there is...
Diabetic retinopathy: early clinical signs and intervention using a Connexin43 modulator

Diabetic retinopathy: early clinical signs and intervention using a Connexin43 modulator

by nata004 | Jul 31, 2018 | Ageing Vision, Physiological optics of the eye, Research

Diabetes is a long-term condition that describes a group of metabolic diseases caused by high sugar levels. In the eye, high blood sugar causes damage to small blood vessels, which swell and may leak fluid. We have identified that even minor blood vessel leakage...
Investigating the age-related alternations of lens physiological optics usring MRI

Investigating the age-related alternations of lens physiological optics usring MRI

by nata004 | Jul 31, 2018 | Ageing Vision, Physiological optics of the eye, Research

The lens physiological optics depends on its water and protein contents. The lens physiological optics alters with ageing, leading to the onset of presbyopia and nuclear cataract. The mechanism behind remains uncertain, owing to lack of non-invasive tools for...
The presbyopia study: using clinical optometry and MRI to study ageing and accommodation in the lens

The presbyopia study: using clinical optometry and MRI to study ageing and accommodation in the lens

by nata004 | Jul 31, 2018 | Ageing Vision, Research

Presbyopia, or the loss of accommodation power of the human lens, leads to the loss of clear near vision in adults >45 years old. This study investigates how the lens changes shape, position, and internal properties as we change viewing distance, and how this...
Identifying early retinal markers of frontotemporal dementia

Identifying early retinal markers of frontotemporal dementia

by nata004 | Jul 31, 2018 | Ageing Vision, Research, Vision Neuroscience

Frontotemporal dementia (FTD) is a leading cause of early onset dementia. It is crucial to identify individuals who are in the early, pre-symptomatic stages of FTD, particularly as treatments are now being developed for neurodegenerative disorders. Imaging of the eye...
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